HOMEVULNERABILITIESCVE-2026-31969
HIGH

CVE-2026-31969

CWE-122Published: March 18, 2026· Updated: Mar 19, 2026

8.1
CVSS v3.1
EPSS:0.04%probability of exploitation in 30 daysPercentile:13.4th

Official Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the `BYTE_ARRAY_STOP` method, an out-by-one error in the `cram_byte_array_stop_decode_char()` function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allocation. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

NVD Source

Technical Analysis

CVE-2026-31969 can be exploited remotely over the network without requiring physical or adjacent access, significantly expanding the attack surface for threat actors.

Exploitation does not require any privileges, though user interaction (Required) is needed, which slightly reduces the risk of mass automated attacks.

A successful exploit results in full integrity compromise (data manipulation), availability disruption (denial of service), with a CVSS base score of 8.1.

CVSS v3.1 Vector Breakdown

Exploitability
Attack VectorNetwork
Attack ComplexityLow
Privileges Req.None
User InteractionRequired
ScopeUnchanged
Impact
ConfidentialityNone
IntegrityHigh
AvailabilityHigh
CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:N/I:H/A:H

Affected Vendors & Products

htslib1 product
htslib
Source: NVD CPE · 2 total CPE entries

Exploit & PoC Resources

NO KNOWN EXPLOITNo public exploit confirmed at this time
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Official Patches & Advisories

All References (2)

Quick Facts

CVE IDCVE-2026-31969
CVSS Score8.1 / 10
SeverityHIGH
WeaknessCWE-122
CISA KEVNo
EPSS (30d)0.04%
Affected1 vendor
PublishedMar 18, 2026

Related CVEs (CWE-122)

Recommended Actions

  • Apply vendor patches immediately
  • Monitor CVE-2026-31969 in threat intel feeds
  • Review IDS/IPS signatures for exploitation attempts
Data sourced from NVD (NIST), CISA KEV, and EPSS (FIRST). Analysis generated by CTIWATCH.COM. CVE data is provided under the NVD usage policy.