CVE-2026-31967
CWE-125Published: March 18, 2026· Updated: Mar 19, 2026
Official Description
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the `cram_decode_slice()` function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
Technical Analysis
CVE-2026-31967 can be exploited remotely over the network without requiring physical or adjacent access, significantly expanding the attack surface for threat actors.
The vulnerability requires no privileges and no user interaction, making it a prime target for automated exploitation campaigns and worm-like propagation.
A successful exploit results in complete confidentiality breach (data exposure), availability disruption (denial of service), with a CVSS base score of 9.1.
CVSS v3.1 Vector Breakdown
Affected Vendors & Products
Exploit & PoC Resources
Official Patches & Advisories
All References (2)
Quick Facts
Related CVEs (CWE-125)
Recommended Actions
- →Apply vendor patches immediately
- →Monitor CVE-2026-31967 in threat intel feeds
- →Review IDS/IPS signatures for exploitation attempts