CVE-2026-31965
CWE-125Published: March 18, 2026· Updated: Mar 19, 2026
Official Description
HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the `cram_decode_slice()` function called while reading CRAM records, validation of the reference id field occurred too late, allowing two out of bounds reads to occur before the invalid data was detected. The bug does allow two values to be leaked to the caller, however as the function reports an error it may be difficult to exploit them. It is also possible that the program will crash due to trying to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.
Technical Analysis
CVE-2026-31965 can be exploited remotely over the network without requiring physical or adjacent access, significantly expanding the attack surface for threat actors.
The vulnerability requires no privileges and no user interaction, making it a prime target for automated exploitation campaigns and worm-like propagation.
A successful exploit results in availability disruption (denial of service), with a CVSS base score of 8.2.
CVSS v3.1 Vector Breakdown
Affected Vendors & Products
Exploit & PoC Resources
Official Patches & Advisories
All References (2)
Quick Facts
Related CVEs (CWE-125)
Recommended Actions
- →Apply vendor patches immediately
- →Monitor CVE-2026-31965 in threat intel feeds
- →Review IDS/IPS signatures for exploitation attempts