CVE-2026-21997
Published: April 21, 2026· Updated: Apr 22, 2026
Official Description
Vulnerability in the Oracle Life Sciences Empirica Signal product of Oracle Life Science Applications (component: Common Core). Supported versions that are affected are 9.2.1-9.2.3. Easily exploitable vulnerability allows low privileged attacker with network access via HTTP to compromise Oracle Life Sciences Empirica Signal. While the vulnerability is in Oracle Life Sciences Empirica Signal, attacks may significantly impact additional products (scope change). Successful attacks of this vulnerability can result in unauthorized creation, deletion or modification access to critical data or all Oracle Life Sciences Empirica Signal accessible data as well as unauthorized read access to a subset of Oracle Life Sciences Empirica Signal accessible data. CVSS 3.1 Base Score 8.5 (Confidentiality and Integrity impacts). CVSS Vector: (CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:C/C:L/I:H/A:N).
Technical Analysis
CVE-2026-21997 can be exploited remotely over the network without requiring physical or adjacent access, significantly expanding the attack surface for threat actors.
Exploitation requires low privileges, which limits the exposure to scenarios where an attacker has already gained initial access.
A successful exploit results in full integrity compromise (data manipulation), with a CVSS base score of 8.5.
The vulnerability has a "Changed" scope, meaning successful exploitation can impact components beyond the vulnerable component itself — such as the host operating system or adjacent services.
CVSS v3.1 Vector Breakdown
Affected Vendors & Products
Exploit & PoC Resources
All References (1)
Quick Facts
Recommended Actions
- →Apply vendor patches immediately
- →Monitor CVE-2026-21997 in threat intel feeds
- →Review IDS/IPS signatures for exploitation attempts